Real-World Safety and Effectiveness of an Initial 0.1 mg Dose of Desmopressin in Older Men with Nocturnal Polyuria

This study provides real-world evidence of effectiveness and safety of oral desmopressin in an older Asian male population, including a subgroup aged older than 80 years. A starting dose of 0.1 mg oral desmopressin, coupled with careful serum sodium monitoring and dose adjustment if required, was associated with significant improvement in all nocturia parameters and a high rate of continuation.