Molecular epidemiology of the expression of urokinase plasminogen activator receptor-associated protein (uPARAP) in mesenchymal malignancies

20260 citationsJournal Articlegold Open Access

Authors

Chao-Chi Wang · VIB-KU Leuven Center for Cancer Biology

Pernille Barkholt · Ascendis Pharma (Denmark)

Agnieszka Woźniak · VIB-KU Leuven Center for Cancer Biology

Ulla Vanleeuw · VIB-KU Leuven Center for Cancer Biology

Che-Jui Lee · VIB-KU Leuven Center for Cancer Biology

Luna De Sutter · VIB-KU Leuven Center for Cancer Biology

Lore De Cock

Abstract

In conclusion, this study highlights the potential of uPARAP as an innovative target for targeted treatments, such as novel antibody-drug conjugates in sarcoma.

Topics & Keywords

Protease and Inhibitor Mechanisms Sarcoma Diagnosis and Treatment Retinoids in leukemia and cellular processes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Translational Oncology

Volume 66, pp. 102708-102708

DOI: 10.1016/j.tranon.2026.102708

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