Radiomic Features Extracted from Magnetic Resonance Imaging to Identify Arteriopathy in a Humanized Mouse Model of Sickle Cell Anemia and Sickle Cell Trait

This study demonstrates feasibility of radiomics in discriminating arterial features between SCD and control mice, and supports radiomics as a non-invasive imaging analytical approach to characterize arterial remodeling in preclinical SCD models, motivating future translational studies linking imaging features to vascular pathology.