Beyond Gram-Negative and Gram-Positive Bacteria: Virulence as a Determinant of Clinical Outcome in Periprosthetic Joint Infections

To our knowledge, this is the first study comparing GN PJIs and GP PJIs based on their virulence, demonstrating that GN PJIs have a significantly worse outcome than GP PJIs. However, high-virulent GP PJIs have shown the same outcome as GN PJIs, suggesting that virulence plays an equally important role in determining the outcome of PJIs.