Brain Sphingolipid and Phospholipid Levels Are Altered in <scp>XK</scp> Disease

20260 citationsJournal Article

Authors

Gabriel Miltenberger-Miltenyi · University of Lisbon

Vasco A. Conceição · University of Lisbon

Klaudia Laborc · Allen Institute for Brain Science

Attila Jones · National Institute on Aging

John Crary · Allen Institute for Brain Science

Claudia De Sanctis · Allen Institute for Brain Science

Emma Thörn ·

Abstract

Our findings provide initial evidence of abnormal sphingolipid and phospholipid concentrations in the brains of XK patients and may provide insights into mechanisms of neurodegeneration in this disease. © 2026 International Parkinson and Movement Disorder Society.

Topics & Keywords

Cellular transport and secretion Lysosomal Storage Disorders Research Sphingolipid Metabolism and Signaling

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: Movement Disorders

DOI: 10.1002/mds.70220

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