Carotid Artery Stenting Outcomes in Comprehensive Stroke Hospitals (CASSH): A Prospective Multicenter Study

Carotid artery stenting performed by fellowship-trained neurointerventionalists at comprehensive stroke centers is associated with low rates of periprocedural stroke, myocardial infarction, and death. These outcomes align with the landmark CREST-2 trial (Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial), particularly in asymptomatic patients, and are strongly influenced by preprocedural disability, stroke severity, age, and cardiac function, underscoring the importance of patient selection and optimized perioperative care.