Probable Tirzepatide-Induced Rhabdomyolysis in an HIV-Positive Patient

Rhabdomyolysis may be a rare but significant adverse effect of tirzepatide, particularly in at-risk populations, such as those with HIV. Clinicians should remain vigilant for rhabdomyolysis in patients presenting with nonspecific symptoms such as muscle pain, fatigue, and dark urine in patients on tirzepatide or other GLP-1 agonists.