SPIRIT–Children and Adolescents (SPIRIT-C) 2026 Extension Statement

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Authors

Ami Baba · Hospital for Sick Children

Maureen Smith · Canadian Respiratory Research Network

Potter Bk · University of Ottawa

An-Wen Chan · University of Toronto

David Moher · University of Ottawa

Alène Toulany · University of Toronto

Amanda Doherty-Kirby ·

Abstract

Inclusion of these SPIRIT-C 2026 items supports comprehensive, meaningful, relevant, and transparent reporting, which can improve both the quality and usefulness of pediatric RCT protocols. RCT protocols contain essential details needed to understand and evaluate the trial's planned aims, design, data collection methods, monitoring, data analysis, and participants' safety.

Topics & Keywords

Pharmaceutical studies and practices Ethics in Clinical Research Meta-analysis and systematic reviews

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: JAMA Pediatrics

DOI: 10.1001/jamapediatrics.2026.0113

Field-Weighted Citation Impact: 41.22