Unique transcriptional profiles of adult human immature neurons in healthy aging, Alzheimer's disease, and cognitive resilience

Following files submitted:1. adult_raw.RDS : Raw seurat object of the processed adult (n=24) snRNA-seq samples.2. adult_filtered.RDS : Filtered (after QC) seurat object of the processed adult (n=24) snRNA-seq samples.3. adultgc_filtered.RDS : Seurat object of adult granule cell subset after additional filtering (See Fig3A). 4. fetal_raw.RDS : Raw seurat object of the processed fetal (n=3) snRNA-seq samples.5. fetal_filtered.RDS : Filtered (after QC) seurat object of the processed fetal (n=3) snRNA-seq samples.6. neurolin.RDS : Seurat object of fetal neurogenic lineage subset (See Fig2D). 7. Functions.R : Helper functions written for running scripts.8. Fig1_script.Rmd : Script to reproduce analysis in Figure 1 and its supplementaries.9. Fig2_script.Rmd : Script to reproduce analysis in Figure 2 and its supplementaries.10. Fig3_script.Rmd : Script to reproduce analysis in Figure 3 and its supplementaries.11. Fig4_script.Rmd : Script to reproduce analysis in Figure 4 and its supplementaries.12. Fig5_script.Rmd : Script to reproduce analysis in Figure 5 and its supplementaries.13. Fig6_script.Rmd : Script to reproduce analysis in Figure 6 and its supplementaries.