Efficacy of long-lasting insecticidal nets before and after the selection of pyrethroid-resistant Anopheles gambiae s.l. and Anopheles funestus s.l. in northeastern Tanzania: A longitudinal meta-analysis of experimental hut trials at a single location

Reduced mortality induced by LLINs after selection of pyrethroid resistance indicates that resistance undermines household control of vector populations. Personal protection indicators such as proportions feeding on blood seemed less affected by the transition to resistance. Meta-analysis, comparing the same net brands before and after selection of resistance, revealed the factors (decreases in mortality, status in blood-feeding rates, and increases in pyrethroid-induced exiting rates) most affected by resistance.