Tumor-specific antibody cocktail treatment suppresses colorectal tumor growth in mice

20260 citationsJournal Articlegold Open Access

Authors

Girja S. Shukla · University of Vermont

Stephanie C. Pero · University of Vermont

Yujing Sun · University of Vermont

Linda Mei · University of Vermont

Ramiro Barrantes-Reynolds · University of Vermont

Matthew R. Fournier · University of Vermont

Margaret E. Ackerman · Dartmouth College

Abstract

Our findings establish a proof-of-concept for individualized, mutation-guided antibody therapies, supporting further development of this approach to improve outcomes in patients with advanced CRC.

Topics & Keywords

Monoclonal and Polyclonal Antibodies Research Immunotherapy and Immune Responses Cancer Cells and Metastasis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer Immunology Immunotherapy

Volume 75, Issue 3

DOI: 10.1007/s00262-026-04337-8

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