Novel APC promoter 1B variant associated with gastric adenocarcinoma and proximal polyposis of the stomach: a case report

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Authors

Jong Sun Park · Ajou University Hospital

Sun Gyo Lim · Ajou University Hospital

Jongmun Choi · Glycemic Index Laboratories

Sae-Mi Lee · Glycemic Index Laboratories

Chang Ahn Seol · Glycemic Index Laboratories

Seon-Yong Jeong · Ajou University Hospital

Eunkuk Park ·

Abstract

This is the first reported case of GAPPS in Korea, associated with a novel likely pathogenic variant in APC promoter 1B, linked to a significant reduction in gene expression.

Topics & Keywords

Genetic factors in colorectal cancer Helicobacter pylori-related gastroenterology studies Metastasis and carcinoma case studies

UN Sustainable Development Goals

Gender equality

Publication Details

Published in: Frontiers in Genetics

Volume 17, pp. 1695311-1695311

DOI: 10.3389/fgene.2026.1695311

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