Protocol for a multicentre target trial emulation comparing ketamine and propofol in critically ill adults undergoing emergency intubation

20260 citationsJournal Articlehybrid Open Access

Authors

Rafael von Hellmann · Dandenong Hospital

Ryan Ruiyang Ling · National University of Singapore

Tapan Parikh aka Parmar · Dandenong Hospital

Abstract

This target trial emulation will provide real-world causal evidence comparing ketamine versus propofol induction for high-risk emergency intubation, with the potential to inform practice, protocols, and future randomised trials.

Topics & Keywords

Anesthesia and Sedative Agents Anesthesia and Neurotoxicity Research Veterinary Pharmacology and Anesthesia

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Critical Care and Resuscitation

Volume 28, Issue 1, pp. 100171-100171

DOI: 10.1016/j.ccrj.2026.100171

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