<i>CERTOMICS</i> : trusted single-cell multiomics pipeline for high-resolution profiling of adoptive cellular immunotherapies

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Authors

Christina Katharina Kuhn · Fraunhofer Institute for Translational Medicine and Pharmacology

David Schmidt · Fraunhofer Institute for Translational Medicine and Pharmacology

Michael Rade · Fraunhofer Institute for Translational Medicine and Pharmacology

Josephine Selke · Fraunhofer Institute for Cell Therapy and Immunology

U Sandy Tretbar · Fraunhofer Institute for Translational Medicine and Pharmacology

Maximilian Merz · Memorial Sloan Kettering Cancer Center

Abstract

Detailed documentation of this pipeline, along with a resource on latest FDA-approved CAR therapies is available on our website: https://fraunhofer-izi.github.io/Living-Drugs-Wiki/. The data underlying this article are available on GitHub at https://github.com/fraunhofer-izi/CERTOMICS. The code is also published on Zenodo at https://doi.org/10.5281/zenodo.18709693.

Topics & Keywords

CAR-T cell therapy research Single-cell and spatial transcriptomics CRISPR and Genetic Engineering

Publication Details

Published in: Bioinformatics

Volume 42, Issue 3

DOI: 10.1093/bioinformatics/btag096

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<i>CERTOMICS</i> : trusted single-cell multiomics pipeline for high-resolution profiling of adoptive cellular immunotherapies

Authors

Abstract

Topics & Keywords

Publication Details