Circulating <scp>microRNAs</scp> as biomarkers in pediatric epilepsy: A longitudinal cohort study

20260 citationsJournal Article

Authors

Licia Salimbene · Bambino Gesù Children's Hospital

Mattia Mercier · Bambino Gesù Children's Hospital

Valentina Spedaletti · Newron Pharmaceuticals (Italy)

Angela De Dominicis · Bambino Gesù Children's Hospital

Costanza Calabrese · Bambino Gesù Children's Hospital

Cristina Filosomi · Bambino Gesù Children's Hospital

Emanuela Angelucci

Abstract

Circulating miRNAs represent promising, minimally invasive biomarkers in pediatric epilepsy. miR-146a-5p may aid etiologic classification, whereas miR-15a-5p and miR-106b-5p could serve as dynamic indicators of disease burden and treatment response, supporting biomarker-driven precision approaches in epilepsy care.

Topics & Keywords

MicroRNA in disease regulation Epilepsy research and treatment Pharmacological Effects and Toxicity Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Epilepsia

DOI: 10.1002/epi.70166

Field-Weighted Citation Impact: 0.00