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BAG Barcelona is formed by 10 groups with a long tradition of accessing the ESRF. The groups belong to three different research institutions: the Institute of Molecular Biology of Barcelona from the Spanish Research Council (IBMB-CSIC), the Institute for Research in Biomedicine from Barcelona (IRB Barcelona) and the Centre for Genomic Regulation (CRG). The main subjects of research from the groups comprise protein/DNA complexes, components of viruses, molecular machines, molecular mechanisms of proteases and other enzymes, de-novo design of protein scaffolds and development of crystallopgrahic methods. The scientific outcomes of all of the groups strongly rely on having acces to high performance beamlines from which to be able to retrieve high-quality structural biology data, both from X-ray crystallography and SAXS experiments. The ESRF offers such excellent performance beamlines together with the exceptional support from their scientific staff.