Impact of Alkaline Phosphatase Normalization on Complication-Free Survival in Primary Biliary Cholangitis

20260 citationsJournal Article

Authors

A. Nagarjuna Reddy · University of Miami

Adrielly Martins · University of Miami

Christopher L. Bowlus · University of California, Davis

Marlyn J. Mayo · The University of Texas Southwestern Medical Center

Elizabeth J. Carey · Mayo Clinic in Arizona

Mark Wong · Banner - University Medical Center Phoenix

Michael Weiss

Abstract

Achieving normal ALP and TB ≤0.6xULN is associated with significantly improved complication-free survival, particularly in high-risk patients. These findings highlight the potential of biochemical thresholds as a meaningful therapeutic goal in PBC management.

Topics & Keywords

Liver Diseases and Immunity Gallbladder and Bile Duct Disorders Pediatric Hepatobiliary Diseases and Treatments

Publication Details

Published in: The American Journal of Gastroenterology

DOI: 10.14309/ajg.0000000000003973

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Impact of Alkaline Phosphatase Normalization on Complication-Free Survival in Primary Biliary Cholangitis

Authors

Abstract

Topics & Keywords

Publication Details