Host biological sex directs immune control of the Plasmodium parasite liver stage in mice

These findings indicate that biological sex- and androgen-mediated differences in baseline hepatic innate immune cell composition critically shape immune responses and parasite survival during <i>Plasmodium</i> liver stage infection. Together, our findings highlight the role of biological sex in shaping immune responses during <i>Plasmodium</i> parasite infection in the liver and underscore the importance of considering sex as a biological variable in malaria research.