Comparative analysis of organic magnesium salts: clinical and pharmacological aspects

Magnesium deficiency is a widespread problem associated with an increased risk of cardiovascular, neurological, and metabolic disorders. The effectiveness of magnesium therapy is largely determined by the bioavailability of the salt used. It is well known that magnesium salts with organic anions are characterized by relatively high bioavailability. This paper presents a detailed analysis of the pharmacological properties of organic magnesium salts: magnesium malate, fumarate, citrate, aspartate, glycinate, threonate, pyroglutamate, orotate, and lactate. The article examines the structural features, elemental magnesium content, anion metabolism, and the effect of anions in the salt on the bioavailability and biodistribution of Mg² + . The feasibility of personalized selection of magnesium salts based on clinical needs is substantiated.