Plasma Biomarkers of Brain Injury in Critically Ill Children Receiving Extracorporeal Membrane Oxygenation

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Authors

Matthew L. Friedman · Indiana University School of Medicine

M. J. Bell · The University of Texas Southwestern Medical Center

Bonnie A. Brooks · Mattel Children's Hospital

Adam S. Himebauch · Children's Hospital of Philadelphia

Asavari Kamerkar · Children's Hospital of Los Angeles

Kerri L. LaRovere · Boston Children's Hospital

Laura L. Loftis

Abstract

Results suggest that GFAP and NfL may be promising candidates for real-time neurologic monitoring in children receiving ECMO and may aid in diagnosis, association with outcomes, and potentially guiding neuroprotective strategies.

Topics & Keywords

Mechanical Circulatory Support Devices Hemoglobin structure and function Immune Response and Inflammation

Publication Details

Published in: JAMA Pediatrics

DOI: 10.1001/jamapediatrics.2026.0015

Field-Weighted Citation Impact: 23.24

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Plasma Biomarkers of Brain Injury in Critically Ill Children Receiving Extracorporeal Membrane Oxygenation

Authors

Abstract

Topics & Keywords

Publication Details