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Work-life balance has emerged as a central theme in modern medicine, particularly in radiology, where high burnout rates underscore the urgency for systemic change. This narrative review explores how perceptions of work-life balance vary across generations-Baby Boomers, Generation X, Millennials, and Generation Z-and how these differences shape workplace expectations and cultural evolution within healthcare. Baby Boomers often view medicine as a vocation requiring sacrifice and long hours, while Gen X emphasises flexibility and independence. Millennials prioritise purpose, inclusivity, and work-life integration, favouring fluid schedules and value-driven environments. Gen Z, as digital natives, seeks ethical workplaces, diversity, and clearly defined personal-professional boundaries. That paper started from a dedicated session at the European Congress of Radiology (ECR) 2025, combining literature references with reflections on evolving professional values. It highlights that while generational perspectives differ, common ground exists: across all groups, well-being, fulfilment, and supportive workplace structures are increasingly seen as essential rather than optional. The paper emphasises the importance of adapting institutional policies to accommodate generational needs through flexible scheduling, mentorship, protected time, and inclusive leadership. Ultimately, we aim for the embracing of intergenerational collaboration and recognition of the diverse definitions of professional success, which are key to building resilient radiology teams. Sustainable solutions must move beyond one-size-fits-all models to foster innovation, prevent burnout, and retain talent across all career stages. It is also calling for healthcare institutions to proactively integrate these perspectives to shape a more supportive and effective professional culture. CRITICAL RELEVANCE STATEMENT: This paper offers a narrative overview of generational perspectives on work-life balance in radiology, highlighting both shared values and evolving priorities across age groups KEY POINTS: Burnout remains a widespread issue in radiology, with high prevalence across all career stages, emphasising the need for systemic solutions rather than individual resilience alone. Generational views on work-life balance vary: Boomers value duty, Millennials seek purpose and flexibility, while Gen Z demands ethics, diversity, and personal sustainability. Intergenerational collaboration and adaptability are essential for building resilient teams, requiring healthcare institutions to embrace diverse expectations and implement inclusive, flexible work models.