A refined approach of the tachypacing porcine model of heart failure

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Authors

Leonhard Berboth · Deutsches Herzzentrum der Charité

Jens Ötvös · Deutsches Herzzentrum der Charité

Alessandro Faragli · Deutsches Herzzentrum der Charité

Beatrice De Marchi · E I L (China)

Gianluigi Longinotti-Buitoni · E I L (China)

Paul Steendijk · Leiden University Medical Center

Philipp Attanasio

Abstract

We established a reliable model of tachypacing-induced HF based on slower pacing and milder progression to HF, while reducing the stress and suffering of the animals.

Topics & Keywords

Cardiomyopathy and Myosin Studies Cardiac electrophysiology and arrhythmias Cardiovascular Function and Risk Factors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Cardiovascular Medicine

Volume 13, pp. 1726438-1726438

DOI: 10.3389/fcvm.2026.1726438

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