Phage–antibiotic synergy restores β-lactam efficacy in MDR Klebsiella quasipneumoniae biofilms and suppresses resistance

20260 citationsJournal Articlediamond Open Access

Authors

Tinatini Tchatchiashvili · Jena University Hospital

Mike Marquet · Jena University Hospital

Ekaterine Gabashvili · Friedrich Schiller University Jena

Kamran A. Mirza · Leibniz Institute of Photonic Technology

Mara Lohde · Jena University Hospital

Christian Brandt · Jena University Hospital

Ralf Ehricht ·

Abstract

Our findings highlight a precision-guided strategy with translational potential for device-associated infections, providing a mechanistic and methodological foundation for optimizing PAS-based therapies.

Topics & Keywords

Bacteriophages and microbial interactions Antibiotic Resistance in Bacteria Cancer Research and Treatments

Publication Details

Published in: Journal of Biomedical Science

Volume 33, Issue 1

DOI: 10.1186/s12929-026-01218-1

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Phage–antibiotic synergy restores β-lactam efficacy in MDR Klebsiella quasipneumoniae biofilms and suppresses resistance

Authors

Abstract

Topics & Keywords

Publication Details