Impact of COVID-19 on inflammatory disease research: a literature analysis of 77,575 PubMed articles

Biomarker research in inflammatory diseases has progressed from molecular inquiry to clinical translation and now to population-level health strategies. The COVID-19 pandemic accelerated this trajectory, positioning biomarkers as pivotal tools that link laboratory science with public health preparedness and policy. Beyond clarifying historical shifts, this study demonstrates how quantitative bibliometric analysis can reveal overlooked relationships between research domains and highlight emerging perspectives. Such findings not only inform scientific agendas but also guide policymakers in strengthening healthcare systems. By framing biomarkers as both scientific markers and societal instruments, this study underscores their transformative role and offers a comprehensive foundation for shaping future investigations.