Effect of Biological Therapy on Symptom Burden and Functional Disability in Patients with Migraine: A Before-and-After Analysis

Biological therapies significantly reduced migraine-related symptom burden and functional disability, including decreases in migraine frequency, pain intensity, and analgesic use, in a Slovenian migraine cohort. These findings support the use of biologics as effective and safe options for migraine prevention in real-world clinical practice.