Clinical feasibility of accelerated whole liver water T1 mapping with T2*-compensation

The developed water T1 (wT1) method enables broad liver coverage in a single 11-s breath-hold. Liver wT1 mapping and the proposed T2*-compensation (wT1_comp) remove the bias in T1 induced by fat and iron, respectively. The analysis in all liver segments allows the assessment of focal liver changes. The proposed liver segments-based wT1_comp method presents potential to identify tissue signal changes associated with fibrosis.