Lactobacillus acidophilus combined with Pediococcus acidilactici ameliorates colitis

The current study demonstrates that the combination of <i>Lactobacillus acidophilus</i> and <i>Pediococcus acidilactici</i> exerts protective effects against colitis in mice by the enhancement of antioxidant capacity, reduced inflammatory responses, preservation of intestinal barrier integrity, and partial restoration of gut microbiota and its metabolite production. Collectively, the study provides novel insights into the synergistic application of the specific probiotic pair for colitis management.