Application of Spider Silk-Based Materials in Regenerative Medicine: From In Vivo Studies to Clinical Use

This review examines the use of spider-silk-based materials in regenerative medicine. Spider silk possesses a unique combination of mechanical and biological properties, making it a promising biomaterial for tissue engineering. An analysis of in vivo studies in animal models and the first clinical trials is presented, demonstrating the ability of spider silk to direct cell growth, accelerate wound healing, and promote peripheral nerve regeneration. The prospects for large-scale production of spider silk and its medical applications are discussed.