Cytokine imbalance and HBV-specific T-cell exhaustion predict disease progression in HIV-HBV coinfection

20260 citationsJournal Articlegold Open Access

Authors

Peter Asaga Mac · Institute of Epidemiology, Disease Control and Research

Dave C. Ibeh · Army Hospital Research and Referral

Mansur Ramalan · Federal University Lafia

Bako A. Ishaku · Federal University Lafia

Abstract

HIV-HBV coinfection was characterized by HBV reactivation, cytokine imbalance, and T-cell exhaustion, which were associated with disease progression and may inform risk stratification.

Topics & Keywords

Hepatitis B Virus Studies Vibrio bacteria research studies Hepatitis Viruses Studies and Epidemiology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Immunology

Volume 17, pp. 1789692-1789692

DOI: 10.3389/fimmu.2026.1789692

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