Impaired mucosal IgA response to SARS-CoV-2 in patients with inborn errors of immunity

20260 citationsJournal Articlegold Open Access

Authors

Fanglei Zuo · Karolinska Institutet

Samaneh Delavari · Tehran University of Medical Sciences

Sima Shokri · Rasool Akram Hospital

Yating Wang · Karolinska Institutet

F Abolnezhadian · Ahvaz Jundishapur University of Medical Sciences

Sara Iranparast · Ahvaz Jundishapur University of Medical Sciences

Fereshte Salami

Abstract

These findings underscore the critical role of mucosal IgA in protection and highlight persistent vulnerability in PAD patients despite IgG replacement therapy.

Topics & Keywords

Immunodeficiency and Autoimmune Disorders Respiratory viral infections research Congenital Ear and Nasal Anomalies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Immunology

Volume 17, pp. 1696834-1696834

DOI: 10.3389/fimmu.2026.1696834

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