Integrated <scp>LC</scp> ‐ <scp>OCT</scp> /Raman Microspectroscopy: A Novel Diagnostic Approach in Ophthalmology Demonstrated in a Case Study

Integrated LC-OCT and Raman microspectroscopy enable the non-invasive identification of conjunctival hydroxyapatite calcifications, providing a dual morphological and molecular diagnostic approach. This bimodal technique successfully identifies microcrystals that are often undetectable by conventional histology due to their solubility and weak birefringence.