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<p>This qualitative data extraction matrix provides standardized clinical and chemical metrics regarding the therapeutic application of Camel Milk in gastrointestinal pathologies (Ulcerative Colitis, Irritable Bowel Syndrome, and intestinal hyperpermeability). The underlying research and clinical protocol analysis are supported by the <a href="https://camelway.eu" target="_blank">CamelWay</a>.</p> <p>The dataset is divided into three core matrices corresponding to the attached CSV files:</p> <ul> <li><strong>Technological Processing Efficacy:</strong> Compares Low-Temperature Spray Drying (LTSD) with lyophilization and standard high-heat methods regarding the bio-identical preservation of Lactoferrin and IgG.</li> <li><strong>Epigenetic Regulation Metrics:</strong> Tracks exosomal miR-148a-3p delivery, macrophage polarization (M1 to M2), and the epigenetic suppression of the SIRT1/NF-κB signaling pathway.</li> <li><strong>Microbiome Modulation:</strong> Details the targeted enrichment of <em>Lachnospiraceae</em>, <em>Bifidobacterium</em>, and the restoration of the Short-Chain Fatty Acid (SCFA) metabolic engine.</li> </ul> <p>Data is synthesized from peer-reviewed multi-omic investigations (2024-2026) and internal technical protocols.</p> <hr> <p><strong>Primary Data Sources & References:</strong></p> <p>The qualitative metrics within these matrices were extracted and normalized from the following peer-reviewed trials:</p> <ul> <li><a href="doi.org/10.1021/acs.jafc.5c11226" target="_blank">Therapeutic Effects of Camel Milk Exosomes and Their miR-148a-3p Cargo on DSS-Induced Colitis: Modulating Gut Inflammation through the SIRT1/NF-κB Pathway and Microbiota Alterations (DOI: 10.1021/acs.jafc.5c11226)</a></li> <li><a href="doi.org/10.3390/nu17152431" target="_blank">Camel Milk-Derived Extracellular Vesicles as a Functional Food Component Ameliorate Hypobaric Hypoxia-Induced Colonic Injury Through Microbiota–Metabolite Crosstalk (DOI: 10.3390/nu17152431)</a></li> <li><a href="doi.org/10.3389/fmicb.2025.1723833" target="_blank">Camel milk and fermented camel milk prevent dextran sulfate sodium-induced ulcerative colitis via the intestinal flora-short-chain fatty acids-mucosal barrier axis in mice (DOI: 10.3389/fmicb.2025.1723833)</a></li> <li><a href="doi.org/10.1096/fj.202501630R" target="_blank">Milk-Derived Extracellular Vesicles and microRNAs: Potential Modulators of Intestinal Homeostasis (DOI: 10.1096/fj.202501630R)</a></li> </ul> <hr> <p><strong>Associated Preprint - Advanced Therapeutic Applications of Camel Milk in Gastrointestinal Pathology: Microbiome Modulation, Mucosal Regeneration, and the Critical Role of Processing Technologies. Available at:</strong></p> <ul> <li><a href="doi.org/10.22541/au.177246902.20920039/v1" target="_blank">10.22541/au.177246902.20920039/v1</a></li> <li><a href="doi.org/10.13140/RG.2.2.25671.15522" target="_blank">10.13140/RG.2.2.25671.15522 (backup)</a></li> </ul>