P211: The mysteries of MYH11: Three unique variants causing thoracic aortic disease

throughout the follow-up; most reports of diarrhea were contained inside the patients' diaper.Adverse events were reported for 3 (42.9%)patients and consisted of pneumonia, sapovirus, and weight loss (n=1 for each, 33.3%). Conclusion:The results of the 7 males with RTT included in this follow-up suggest that the real-world benefits and tolerability of trofinetide in males follow similar trends with the general population of LOTUS.