Quantitative analysis of venous flow distribution and pulsatile near arteriovenous crossings assessed by Doppler OCT flowmetry

Conventional fundus photography represents retinal vessels in two dimensions, precluding visualization of three-dimensional velocity distributions and quantification of local blood-flow mechanics at arteriovenous (AV) crossings. Using a Doppler OCT blood flowmeter, venous intravascular velocity profiles were extracted at AV crossings, and wall shear stress (WSS) was quantified. In this study, we report the physiological range of WSS at AV crossings in healthy eyes and systematically evaluate within-day repeatability and day-to-day reproducibility of these OCT-derived hemodynamic measurements.