Vericiguat as a Novel Ferroptosis Inhibitor Alleviates Doxorubicin‐Induced Cardiotoxicity

20260 citationsJournal Article

Authors

Huan Han · Zhujiang Hospital

Tao Luo · Zunyi Medical University

C X Liu · Zhujiang Hospital

Wen Ou · Third Affiliated Hospital of Southern Medical University

Y. Zhang · Zhujiang Hospital

Zhiyin Zhang · Fuwai Yunnan Cardiovascular Hospital

Zhiyin Zhang ·

Abstract

These findings indicate that vericiguat protects against doxorubicin-induced myocardial ferroptosis, positioning it as a promising therapeutic candidate for DIC and a novel ferroptosis inhibitor.

Topics & Keywords

Ferroptosis and cancer prognosis Ferrocene Chemistry and Applications Cancer, Lipids, and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Basic & Clinical Pharmacology & Toxicology

Volume 138, Issue 4, pp. e70219-e70219

DOI: 10.1111/bcpt.70219

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