Maternal and Perinatal Outcomes of Live Births After Uterus Transplantation: A Systemic Review

( Acta Obstet Gynecol Scand . 2025;104:559-578. doi: 10.1111/aogs.15003.) Absolute uterine factor infertility (AUFI) is caused by either the complete anatomic absence of a uterus or the inability of the uterus to support a viable pregnancy. This condition has justifiably been the hardest challenge for fertility specialists to overcome. However, uterine transplantation (UTx) has recently been successful in meeting this challenge. Transplantation of a uterus is complicated and requires many other factors before a pregnancy can be attempted, and pregnancy itself places risk on both the mother and the fetus. This study aimed to evaluate maternal and neonatal outcomes of women who achieved pregnancy following a UTx.