Impact of Germline <i>BRCA</i> Mutation Status on Antitumor Activity of Modified FOLFIRINOX in Patients With Advanced Pancreatic Cancer: An Exploratory Analysis

g<i>BRCA</i> mutation status was strongly associated with enhanced radiologic and biological responses to mFFX in APC. Routine screening for g<i>BRCA</i> mutations may provide essential guidance in therapeutic decision making and substantially improve clinical outcomes in this population.