The Relationship Between Y‐90 and Bleeding Frequency in Haemophilic Synovitis of the Knee: A Systematic Review

The conclusions of this systematic review are constrained by the absence of randomised studies and the risk of bias of the included observational studies. From an evidence-based medicine perspective, there is insufficient evidence to support Y-90 RSV reducing bleeding in haemophilic knees. This review identifies a need for at least high-quality observational studies to justify this intervention.