REAL208, a Liposome-based Formulation of Phosphodiesterase Inhibitor, Protects Acute Kidney Deficiency in Mice

These findings demonstrated that liposomal dipyridamole exerts robust renoprotective effects by preserving mitochondrial function, suppressing oxidative stress, and attenuating inflammation. REAL208 represents a promising therapeutic strategy for AKI and warrants further translational and clinical investigations.