Optimized Detection of Left Ventricular Hyperpolarized [1‐ <sup>13</sup> C]Pyruvate Signal in Human Cardiac Metabolic Imaging

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Authors

Fatemeh Khashami · Advanced Imaging Research (United States)

Ivan Dimitrov · Philips (United States)

Maximilian Füetterer · ETH Zurich

Stefan Glöggler · Advanced Imaging Research (United States)

Bei Zhang · Advanced Imaging Research (United States)

Egzona Tan · The University of Texas Southwestern Medical Center

Sebastian Kozerke

Abstract

A mathematical model using exponential fitting and thresholding of the intensity distribution of [1-<sup>13</sup>C]pyruvate signal in the LV blood pool provides a strong correlation with the metabolic outcome, allowing for a semiautomated method to robustly assess the left ventricular pyruvate signal in dynamic nuclear polarization studies.

Topics & Keywords

Advanced NMR Techniques and Applications Advanced MRI Techniques and Applications Atomic and Subatomic Physics Research

Publication Details

Published in: Magnetic Resonance in Medicine

DOI: 10.1002/mrm.70332

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Optimized Detection of Left Ventricular Hyperpolarized [1‐ <sup>13</sup> C]Pyruvate Signal in Human Cardiac Metabolic Imaging

Authors

Abstract

Topics & Keywords

Publication Details