Structural and Microvascular Changes in Demyelinating Optic Neuritis Assessed by OCT and OCTA: A 6-Month Longitudinal Study

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Authors

Sofia Bezerra · Universidade do Porto

Rita Teixeira-Martins · Hospital de São João

Margarida Ribeiro · Universidade do Porto

Paulo Marcos Brasil Rocha · Hospital de São João

Olinda Faria · Universidade do Porto

Joana Guimarães · Universidade do Porto

Amândio Rocha-Sousa ·

Abstract

Demyelinating optic neuritis exhibits a dynamic course with early structural thickening followed by progressive neuroaxonal loss. Significant longitudinal pRNFL and ONH thinning supports sustained axonal degeneration beyond the acute phase. OCTA changes were restricted to selected peripapillary sectors, suggesting subtle parallel microvascular alterations. OCT and OCTA offer complementary information for comprehensive assessment and monitoring of demyelinating optic neuropathies.

Topics & Keywords

Multiple Sclerosis Research Studies Peripheral Neuropathies and Disorders Intraoperative Neuromonitoring and Anesthetic Effects

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Clinical ophthalmology

Volume Volume 20, pp. 1-11

DOI: 10.2147/opth.s569321

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