Antibiotic exposure in early childhood and its impact on gut microbial balance and immune dysregulation

Antibiotic exposure in early childhood has been linked to lasting changes in gut microbial balance and immune system dysregulation, contributing to an increased risk of immune-related diseases. Therefore, it is of interest to investigate the long-term effects of early-life antibiotic use on gut microbiota composition, immune markers and the prevalence of conditions such as asthma and food allergies. Fecal and blood samples were analyzed to assess microbial diversity and immune function in antibiotic-exposed and non-exposed children. Results showed significant differences in microbial diversity, inflammatory cytokine levels and immune markers between the groups. These findings advance knowledge by highlighting the critical role of early antibiotic exposure in shaping immune health and chronic disease susceptibility later in life