Evaluating the Role of VELscope in Oral Cancer and Pre-Cancer Screening: A Scoping Review

VELscope serves as a valuable adjunctive tool to COE, improving lesion detection in high-risk populations. However, its standalone diagnostic use is limited due to low specificity. Targeted clinician training and integration into multimodal screening protocols are essential to optimize its clinical utility. Further studies are warranted to assess its clinical effectiveness in community-based cancer screening among high-risk population with behavioural risk factors, as well as to conduct cost-effectiveness analyses.