Latin American HECAP Physics Briefing Book 2025

The first process for the Latin American Strategy Forum for Research Infrastructure for High Energy, Cosmology and Astroparticle Physics (LASF4RI-HECAP) came to a conclusion in October 2020, with a Physics Briefing Book (PBB) presented in (2104.06852). Here we present an updated PBB, the result of the first update of LASF4RI-HECAP. The update process began with a call for White Papers from the HECAP community. The submitted contributions were presented at the III LASF4RI for HECAP Symposium: Update of the Strategic Plan, held at ICTP-SAIFR in São Paulo in August 26-29, 2024, with the participation of the Preparatory Group, High Level Strategy Group, Funding Agencies and representatives of similar efforts from around the globe. This updated PBB was written by the Preparatory Group based mainly on 46 White Papers submitted by the community and is organized around seven working groups: Astronomy, Astrophysics and Astroparticle Physics; Cosmology; Dark Matter; Neutrinos; Electroweak and Strong Interactions, Higgs Physics, CP and Flavour Physics and BSM; Instrumentation and Computing; Advanced Training and Capacity Building. It is intended to provide the essential input for the creation of a long-term HECAP strategy in the region.