Landscape of somatic mutations in a large cohort of Chinese patients with immune dysregulations

20260 citationsJournal Article

Authors

Jiemin Fu · Sir Run Run Shaw Hospital

Qiang Fu · Shanghai Jiao Tong University

Jun Wang · Sir Run Run Shaw Hospital

Qintao Wang · Sir Run Run Shaw Hospital

Liang Zhang · Central South University

Huihui Chi · Shanghai Jiao Tong University

Lei Zhang ·

Abstract

This study delineated the genetic landscape of pathogenic somatic mutations underlying autoinflammatory and autoimmune diseases, offering valuable insights for genetic diagnosis and targeted therapies.

Topics & Keywords

Immunodeficiency and Autoimmune Disorders Inflammasome and immune disorders Otitis Media and Relapsing Polychondritis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Arthritis & Rheumatology

DOI: 10.1002/art.70126

Field-Weighted Citation Impact: 0.00