Integrative analysis reveals luteolin’s molecular targets and mechanisms in pancreatic cancer treatment

20260 citationsJournal Articlegold Open Access

Authors

Danhong Pan · The First People's Hospital of Wenling

Shixia Li · Taizhou University

Peixi Zhong · Taizhou University

Lili Chen · The First People's Hospital of Wenling

Binbo Fang · Taizhou University

Yifu Feng · Taizhou Central Hospital

Abstract

This study identifies MET as a critical therapeutic target of luteolin in pancreatic cancer, providing mechanistic insights into luteolin's anti-cancer effects via the MET/PI3K/AKT signaling pathway and supporting its potential clinical application.

Topics & Keywords

FOXO transcription factor regulation Cancer Cells and Metastasis Liver physiology and pathology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European journal of medical research

DOI: 10.1186/s40001-026-04056-x

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