Synergizing Lean Healthcare and Industry 4.0 Technologies for Sustainable Healthcare Transformation: A Literature Review

Due to the significant challenges faced by healthcare systems, medical establishments strive to set the tone by integrating new concepts to bridge this gap. Here, Lean Healthcare (LH) has been inspired by Lean Management (LM). Utilizing LM to optimize industrial processes and reduce waste presented a real opportunity to enhance the quality of medical services. For more improvement, healthcare systems pushed themselves to keep up with progress by implementing Industry 4.0 (I4.0) tools, such as IoT, Big Data analytics, and AI with LH and sustainability practices. The results promised better quality of care. Although this concept offers significant potential for more efficient workflows and optimizing medical processes, studies examining their combined implementation are still scarce. This research fills the gap via a literature review (LR) of peer-reviewed articles published between 2015 and 2025. The review investigates the impact of integrating smart technologies into LH frameworks and highlights how LH contributes to sustainability across multiple dimensions: economic, social, technological and environmental. Key findings show the impact of combining advanced tools with lean principles by reducing waiting times (25%) and length of stay while also improving satisfaction. Sustainability-centered adaptations of LH incorporate social and environmental comparative parameters such as resource consumption, for instance, reducing operational costs by up to 30–40%. Many challenges were faced with this implementation, such as cultural, technical challenges (e.g., complexity of integration with digital systems), and sustainability barriers. However, to overcome these barriers, this paper proposes a holistic implementation that aligns lean processes with organizational change and sustainability goals.