Maternal Acetaminophen Use and Child Neurodevelopment

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Authors

Pei‐Chen Lee · National Cheng Kung University

Yu-Hsuan Chuang · National Cheng Kung University

Ya-Hui Hu · National Cheng Kung University

Chia-Ni Lin · National Cheng Kung University

Chung-Yi Li · National Cheng Kung University

Ying-Yeh Chen · National Yang Ming Chiao Tung University

Julia E. Heck

Abstract

The findings of this cohort study in Taiwan suggest that positive associations were observed between maternal prenatal acetaminophen prescriptions and offspring's ADHD or ASDs in the full cohort but not in the sibling-matched analyses. A substantial divergence in associations in the sibling bidirectional analyses indicates unaddressed sources of bias and prevents firm conclusions from being drawn using the sibling design.

Topics & Keywords

Pregnancy and Medication Impact Prenatal Substance Exposure Effects Pharmacological Effects and Toxicity Studies

Publication Details

Published in: JAMA Pediatrics

DOI: 10.1001/jamapediatrics.2026.0071

Field-Weighted Citation Impact: 0.00

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Maternal Acetaminophen Use and Child Neurodevelopment

Authors

Abstract

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Publication Details