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The interplay between migration, regional economic growth and unemployment has emerged as a central concern in contemporary macroeconomic and legal discourse. While labor mobility is a primary driver of national and global prosperity, fueling innovation and industrial production, it frequently exerts significant pressure on regional labor ecosystems and public infrastructure. This tension creates a paradox where the drive for economic expansion may inadvertently threaten social stability and the fundamental right to an adequate standard of living for both host and migrant populations. This article explores how regional policy and international frameworks seek to reconcile the economic necessity of labor mobility with the requirement for localized labor market equilibrium. Drawing on interdisciplinary perspectives from regional economics and international law, the study employs cost-benefit analysis (CBA) and sustainable development frameworks to examine the legal principles and economic tools required for an equitable transition in shifting labor markets. The objective of this research is to propose a normative framework wherein "sustainable regional development" is defined as the seamless integration of economic growth, labor market stability, and the protection of human dignity. By identifying mechanisms through which migration can be managed as a strategic asset rather than a disruptive force, the study emphasizes the need for a balanced approach. Ultimately, the article argues that managing these trade-offs through international cooperation and robust regulatory mechanisms is essential for fostering a regional development path that is resilient, equitable, and capable of sustaining long-term prosperity.