Monosialoganglioside‐Containing Nanoliposomes Protect Against Acute and Chronic Ischemic Stroke Injury

20260 citationsJournal Articlegold Open Access

Authors

Saif Ahmad · St. Joseph's Hospital and Medical Center

Takuma Maeda · St. Joseph's Hospital and Medical Center

Jessica Contreras · St. Joseph's Hospital and Medical Center

Nina Karamanova · Phoenix VA Health Care System

Kaleb Morrow · Phoenix VA Health Care System

Sudhanshu P. Raikwar · Phoenix VA Health Care System

Naseem Akhter

Abstract

Treatment of mice with NLGM1 resulted in reduced brain infarct size acutely following intraluminal MCAO and improved motor and behavior function acutely and chronically following intraluminal and PT MCAO. NLGM1 represents a promising novel neuroprotective agent in stroke.

Topics & Keywords

Glycosylation and Glycoproteins Research Advanced Glycation End Products research Magnolia and Illicium research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of the American Heart Association

Volume 15, Issue 6, pp. e042974-e042974

DOI: 10.1161/jaha.125.042974

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